RASCANDIS 1.0 Form: Therapeutic Approach of Systemic Anti-Candidiasis for Non-Transplant Patients

RASCANDIS 1.0 Form: Therapeutic Approach of Systemic Anti-Candidiasis for Non-Transplant Patients

Authors

  • Ronald Irwanto Natadidjaja Department of Internal Medicine, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia
  • Aziza Ariyani RASPRO Indonesia Study Group
  • Hadianti Adlani RASPRO Indonesia Study Group
  • Anti Dharmayanti Department of Clinical Pathology, Fatmawati Central General Hospital, Jakarta, Indonesia
  • Joyce Bratanata Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Tzu Chi Hospital, Pantai Indah Kapuk, Jakarta, Indonesia

Keywords:

systemic anti-candidiasis, non-transplant, RASCANDIS 1.0, appropriately

Abstract

It has been a concern that using antifungals may induce some fungi to develop antifungal resistance in the future. Therefore, systemic anti-candidiasis agents should become a focus in controlling antifungal drugs since it is quite commonly used. There are currently three approaches to using systemic anti-candidiasis agents based on their indication, i.e. definitive, empiric and pre-emptive indication. These can be applied by observing supportive findings such as the presence of Candida sp infection or colonization, the severity of the infection and the patient's risk factors. The severity of invasive candidiasis is usually severe, and various risk factors need to be considered, such as Total Parenteral Nutrition (TPN), catheterization including deep vein catheter, central venous catheter (CVC), etc. 

Antifungal stewardship program, including management of systemic anti-candidiasis, is essential nowadays. Therefore, it is necessary to have a program that can serve as a guideline for clinicians to implement a treatment approach for systemic anti-candidiasis. RASPRO Alur Anti Candida Sistemik (RASCANDIS) 1.0 form or the Indonesian Regulation on the Prospective Antimicrobial System on Systemic Anti-Candidiasis Flowchart 1.0 form is an actual implementation to provide guidelines for clinicians to administer systemic anti-candidiasis agents for non-transplant patients. The form is not a diagnostic tool, but it is more likely to serve as a review and summary of knowledge obtained from various scientific journals, which is expected that it can be proposed as an effort to administer therapeutic management of systemic anti-candidiasis appropriately.

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Published

2023-04-30

How to Cite

1.
Natadidjaja RI, Ariyani A, Adlani H, Dharmayanti A, Bratanata J. RASCANDIS 1.0 Form: Therapeutic Approach of Systemic Anti-Candidiasis for Non-Transplant Patients. J Biomedika dan Kesehat [Internet]. 2023 Apr. 30 [cited 2023 Dec. 7];6(1):133-41. Available from: https://jbiomedkes.org/index.php/jbk/article/view/344

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Review Article
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